About 8 results found for searched term "SD-06" (0.182 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M7558 | SD-06 | p38 MAPK |
| SD-06 is a p38 MAP kinase inhibitor; inhibits p38α with an IC50 value of 170 nM and inhibits LPS-stimulated TNF-release in rats (83% inhibition at 1mg/kg, po). IC50 value: 170 nM Target: p38MAPK | ||
| M5748 | MSDC-0602 | PPAR |
| Azemiglitazone; MSDC0602 | ||
| Azemiglitazone (MSDC-0602) is a PPARγ -retained thiazolidindione (TZD) that interacts with mitochondrial pyruvate vector (MPC) and inhibits its activity. | ||
| M30982 | DPI 201-106 | Sodium Channel |
| SDZ 201106 | ||
| DPI 201-106 (SDZ 201106) is a cardiotonic agent with a synergistic sarcolemmal and intracellular mechanism of action. DPI 201-106 shows cardioselective modulation of voltage-gated sodium channels (VGSCs) resulting in a positive inotropic effect. | ||
| M40989 | Azemiglitazone potassium | PPAR |
| MSDC-0602K | ||
| Azemiglitazone potassium is a thiazolidinediones that binds to PPARγ with an IC50 value of 18.25 μM. It also modulates the mitochondrial pyruvate carrier (MPC). It can be used in studies related to non-alcoholic steatohepatitis (NASH). | ||
| M9924 | Risdiplam | DNA/RNA Synthesis |
| RG7916; RO7034067 | ||
| Risdiplam (also known as RG7916 and RO7034067) is a gene splicing modulator (neuromuscular disease) that distributes into the central nervous system (CNS) and peripheral tissues. | ||
| M15044 | Recombinant Human SDF-1α/CXCL12 (E. coli) | Recombinant Proteins |
| SDF-1-α; SDF1α; CXCL-12 | ||
| Stromal cell-derived factor-1 α / CXCL12 (SDF-1α) and SDF-1β are members of the α subfamily of chemokines, lacking the ELR domain. Protein construction: SDF-1α/CXCL12 (Lys22-LYS89), Accession # P48061. | ||
| M21429 | Recombinant Human SDF-1β/CXCL12 (E. coli) | Recombinant Proteins |
| SDF1β; SDF-1 beta; CXCL-12 | ||
| Stromal cell-derived factor-1β (SDF-1β), also known as SCYB12, PBSF, and CXCL12, is an 8.3 kDa, heparin-bound member of the CXC(or α) chemokine family that signals via the CXCR4 receptor. Protein Construction: SDF-1β/CXCL12 (Lys22-Met93). Accession # P48061. | ||
| M28874 | PF-06952229 | TGF-β Receptor |
| PF-06952229 is a potent, selective and orally active TGFbR1 inhibitor. PF-06952229 specifically binds to TGFbR1 and prevents TGFbR1-mediated signal transduction. PF-06952229 is a promising antineoplastic agent for the study solid tumors, especifically metastatic breast cancer. | ||
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